This paper introduces an “hypothesis about the growth pattern of the secondary ossification centre (SOC)”, whereby two phases are assumed. First, the formation of cartilage canals as an event essential for the development of the SOC. Second, hence the canals are merged in the central zone of the epiphysis, molecular factors are released (primarily Runx2 and MMP9) spreading and causing hypertrophy of adjacent cells. In order to test this hypothesis we solve a system of coupled partial differential equations using the finite element method and we have obtained spatio-temporal patterns of the growth process of the SOC. The model is in qualitatively agreement with experimental results previously reported by other authors.

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