During cardiac c-looping, an important developmental phase in early heart development, the initially straight heart tube (HT) is transformed into a c-shaped tube. Two distinct processes, ventral bending and dextral rotation, constitute c-looping. Previous research suggests that ventral bending is likely driven by forces that are intrinsic to the heart while dextral rotation is driven by forces applied by a pair of omphalomesenteric veins that flank the heart tube and a membrane called the splanchnopleure that lies on top of the heart.
- Bioengineering Division
Study of Beloussov’s Hyper-Restoration Hypothesis for Regulation of Embryonic Heart Bending
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Ramasubramanian, A, & Taber, LA. "Study of Beloussov’s Hyper-Restoration Hypothesis for Regulation of Embryonic Heart Bending." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 63-64. ASME. https://doi.org/10.1115/SBC2010-19260
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