Response of an Actin Filament Network Model Under Cyclic Stretching Through a Coarse Grained Monte Carlo Approach Available to Purchase

The cytoskeleton is a dynamic system linked to the cell’s environment through sites of potential mechanical interaction such as focal adhesions, integrins, cellular junctions, and the extracellular matrix. The physiologic mechanical stimulation experienced by cells such as endothelial cells is comprised of multiple mechanical modes (e.g., stretching and shear), thus presenting a challenge to characterize their influence on cell structure.