Blunt and penetrating liver injuries make up one-third of all abdominal injuries, and 5% of all trauma admissions are due to injuries to this organ . Additionally, the majority of blunt liver injuries stem from motor vehicle crashes (Moore 2004). Validated computational models of liver are useful for understanding injury to the liver from mechanical loading. It has been shown previously that the mechanical behavior of perfused ex vivo liver closely approximates the in vivo behavior, while unperfused ex vivo liver response differs significantly from the in vivo case . Therefore, to achieve a realistic approximation of in vivo liver mechanics for injury prediction, it is beneficial to adopt a constitutive model for liver that incorporates both fluid and solid phases of the tissue, to reflect this perfusion effect.
- Bioengineering Division
Poroviscoelastic Modeling of Perfused Bovine Liver Tissue
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Raghunathan, S, Evans, D, & Sparks, J. "Poroviscoelastic Modeling of Perfused Bovine Liver Tissue." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 295-296. ASME. https://doi.org/10.1115/SBC2010-19054
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