Regional lung deformation (as opposed to whole lung volume change) may be an indicator of localized lung malformations. Regional deformation may be characterized by principal strains, but lack a direct physiological relevance. Alternatively, regional volume change (distribution of Jacobian) is physiologically intuitive, but does not characterize all aspects of deformation. For instance, a region may undergo no volume change, but still have deformed significantly — say, when the lengthening in one direction is compensated by contraction along another direction. From a perspective of physiological relevance to lung function, lung deformation may be thought to encompass both the volume change and directional preferences in volume change.
- Bioengineering Division
A Novel Method of Characterizing Regional Lung Deformation
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Amelon, R, Cao, K, Ding, K, Christensen, GE, Reinhardt, JM, & Raghavan, M. "A Novel Method of Characterizing Regional Lung Deformation." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 259-260. ASME. https://doi.org/10.1115/SBC2010-19578
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