An accurate model of the human respiratory system allows health scientists to gain insight into the interactions between particulate matter (PM) and the exposed surfaces of the lung airways. Respiratory dose simulations and modeling are frequently used for evaluating health effects of inhaled toxic substances [1–4] and for analyzing the risk potentials of inhaled toxic or harmful PM such as vehicle emissions [4,5]. Pharmaceutical companies and pulmonologists find it useful in evaluating efficacy of inhaled medicinal aerosols and devising new patient treatment regimen [6–8], especially in vulnerable population groups such as children, industrial workers, and the elderly [10]. Recently, the respiratory system has seen increased attention as a possible venue for drug delivery to fight diseases such as AIDS, diabetes, and various cancers, among others. Computational fluid dynamics modeling and simulation continues to be an important tool for understanding of delivery of pharmaceutical aerosols to the lung airways and thereby improving treatment of airway disease, particularly, asthma with bronchodilators and corticosteroids inhalers [11,12].
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ASME 2010 Summer Bioengineering Conference
June 16–19, 2010
Naples, Florida, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4403-8
PROCEEDINGS PAPER
Computational Modeling of Aerosol Deposition Characteristics in Cyclic Bifurcating Tube Flow
Chong S. Kim
Chong S. Kim
U. S. Environmental Protection Agency, Research Triangle Park, NC
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Sinjae Hyun
Mercer University, Macon, GA
Sun Jin Moon
Mercer University, Macon, GA
Chong S. Kim
U. S. Environmental Protection Agency, Research Triangle Park, NC
Paper No:
SBC2010-19169, pp. 255-256; 2 pages
Published Online:
July 15, 2013
Citation
Hyun, S, Moon, SJ, & Kim, CS. "Computational Modeling of Aerosol Deposition Characteristics in Cyclic Bifurcating Tube Flow." Proceedings of the ASME 2010 Summer Bioengineering Conference. ASME 2010 Summer Bioengineering Conference, Parts A and B. Naples, Florida, USA. June 16–19, 2010. pp. 255-256. ASME. https://doi.org/10.1115/SBC2010-19169
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