The constant flow of aqueous humor (AH) in the anterior eye provides avascular tissues, notably the lens and cornea, with oxygen and nutrients (Fig. 1a). The hydrodynamics of AH and the iris contour are directly related to each other and abnormality of one may cause abnormal behavior in the other one. For example, in primary angle closure glaucoma, the abnormal anteriorly-located iris blocks the outflow pathway of AH. Increased AH pressure, in return, may push the iris more towards the anterior and worsen the blockage.

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