Red blood cells (RBCs) or erythrocytes are biconcave disks with diameter of 8μm and thickness of 2 μm. RBC can be considered as a nucleus free deformable capsule enclosed by a flexible membrane and consisting of an incompressible viscous fluid [8, 9]. The deformation of RBCs is thought to play a major role in both RBC dynamics and functionality. Previous studies have indicated that two important characteristics related to deformation of the RBC [1]: i) the interior of the RBC is a liquid state that surrounded by an elastic membrane, ii) the biconcave shape of the RBC enables it to deform into a wide varieties of shapes without inducing any stresses in the cell membrane.

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