While heart valve prostheses have been used successfully since 1960, outcomes are far from ideal. The underlying problem with bioprostheses is a limited life from structural changes such as calcification and leaflet wear, leading to valve failure. The underlying problem with mechanical heart valves is the presence of flow disturbances which necessitate anticoagulation. A polyurethane valve has the potential to improve upon the shortcomings of existing valves and ultimately improve patient survival.

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