Aqueous humor (AH) constantly flows in the anterior eye to provide avascular tissues, notably the lens and cornea, with oxygen and nutrients. If AH outflow is impeded, the normal intraocular pressure could reach to dangerous levels. In angle closure, the abnormal shape and position of the iris is directly related to the blockage of the outflow. In particular, when the peripheral iris moves forward, it may narrow or close the angle between the iris and cornea, where most of AH leaves the anterior eye.

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