Aqueous humor (AH) constantly flows in the anterior eye to provide avascular tissues, notably the lens and cornea, with oxygen and nutrients. If AH outflow is impeded, the normal intraocular pressure could reach to dangerous levels. In angle closure, the abnormal shape and position of the iris is directly related to the blockage of the outflow. In particular, when the peripheral iris moves forward, it may narrow or close the angle between the iris and cornea, where most of AH leaves the anterior eye.
- Bioengineering Division
The Effect of the Posterior Location of the Dilator on the Iris Concavity
Amini, R, Whitcomb, JE, Al-Qaisi, MK, Akkin, T, & Barocas, VH. "The Effect of the Posterior Location of the Dilator on the Iris Concavity." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 973-974. ASME. https://doi.org/10.1115/SBC2009-205186
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