Computational models can be used to predict the blood pressure and blood flow in a region of interest within the vascular system. A computational model includes a region of interest geometry and boundary conditions. The outlet boundary conditions not only need to reflect the downstream network of vessels, but also the dynamic nature of the downstream network. An example of this is the pulmonary vasculature, which has arterioles that dilate and constrict during the respiratory process altering the resistance/impedance of the downstream network [1]. In order to accurately model a system with a dynamic change, such as the pulmonary system, a dynamic boundary condition should be utilized.

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