Aging of the skin is a universal process. Well-known characteristics are the development of fine lines and wrinkles, but also changes in skin tone, skin texture, thickness and moisture content are aspects of aging [1,2]. The aging process can be divided into intrinsic aging, such as changes in e.g. dermal components like collagen, elastic fibers, glucosaminogycans and fibroblasts, and extrinsic aging, which is caused by external factors e.g. damage by UV-radiation [3]. Rejuvenation of the skin aims at reversing the intrinsic and extrinsic signs of skin aging and can be established in the epidermis as well as in the dermis.

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