An aneurysm is a localised persistent dilation of the blood vessel wall. Aneurysm formation is hypothesised to be a consequence of haemodynamically generated forces working on the arterial wall leading to degeneration of the media layer (1). This focal degeneration typically occurs at curved arterial segments and at bifurcation points around the circle of Willis. Intracranial aneurysms are traditionally classified by aetiology and morphology. The majority are idiopathic and saccular. It is estimated that 1.5–6% of the general population have or will develop an intracranial aneurysm, predominantly occurring in women, most of them being asymptomatic (1). If left undetected these aneurysms may rupture with a 30 day mortality rate of 45% (1). There are two treatment options surgical clipping or endovascular coiling. Both of these techniques exclude the aneurysm from the normal circulation. Endovascular coiling is preferred due to its minimally invasive nature. Numerous studies have been done so far based on idealized glass models and using FVM, FEA methods, but very little testing has been carried out on devices using realistic silicone models. This is mainly because of the complexity of the cerebral vasculature. Silicone replicas of both realistic and idealised models were manufactured based on CT scans and anatomical dimensions obtained from literature, respectively (2).
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ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Generation of Realistic Physical Models of Cerebral Aneurysms for In Vitro Flow Visualisation Available to Purchase
Paul Fahy,
Paul Fahy
Galway Mayo Institute of Technology, Galway, Ireland
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Tim McGloughlin,
Tim McGloughlin
University of Limerick, Limerick, Ireland
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Patrick Delassus,
Patrick Delassus
Galway Mayo Institute of Technology, Galway, Ireland
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Liam Morris
Liam Morris
Galway Mayo Institute of Technology, Galway, Ireland
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Paul Fahy
Galway Mayo Institute of Technology, Galway, Ireland
Tim McGloughlin
University of Limerick, Limerick, Ireland
Patrick Delassus
Galway Mayo Institute of Technology, Galway, Ireland
Liam Morris
Galway Mayo Institute of Technology, Galway, Ireland
Paper No:
SBC2009-206656, pp. 841-842; 2 pages
Published Online:
July 19, 2013
Citation
Fahy, P, McGloughlin, T, Delassus, P, & Morris, L. "Generation of Realistic Physical Models of Cerebral Aneurysms for In Vitro Flow Visualisation." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 841-842. ASME. https://doi.org/10.1115/SBC2009-206656
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