This paper is one of the components of our research on how to optimize polymeric drug delivery vehicles. One of the applications is in the topical delivery of anti-human immunodeficiency virus (HIV) gels called microbicides [1]. Microbicides are delivered to vaginal or rectal epithelium to protect it from HIV and other sexually transmitted infections. Microbicides may provide a physical barrier amplifying the normal vaginal defense, as well as destroy the pathogens chemically or inhibit viral infection. The microbicide may consist of an anti-HIV active agent in some delivery vehicle, such as a gel, cream or foam. Microbicides are a promising solution to provide a low-cost, female-controlled method for protection against HIV and other sexually transmitted pathogens.
Skip Nav Destination
ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
The Effect of Surface Tension on the Epithelial Spreading of Non-Newtonian Drug Delivery Vehicles: Numerical Simulations
Sarah L. Kieweg
Sarah L. Kieweg
University of Kansas, Lawrence, KS
Search for other works by this author on:
Bin Hu
University of Kansas, Lawrence, KS
Sarah L. Kieweg
University of Kansas, Lawrence, KS
Paper No:
SBC2009-206565, pp. 833-834; 2 pages
Published Online:
July 19, 2013
Citation
Hu, B, & Kieweg, SL. "The Effect of Surface Tension on the Epithelial Spreading of Non-Newtonian Drug Delivery Vehicles: Numerical Simulations." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 833-834. ASME. https://doi.org/10.1115/SBC2009-206565
Download citation file:
6
Views
Related Articles
Peptide- and Aptamer-Functionalized Nanovectors for Targeted Delivery of Therapeutics
J Biomech Eng (July,2009)
Experimental and Numerical Models of Three-Dimensional Gravity-Driven Flow of Shear-Thinning Polymer Solutions Used in Vaginal Delivery of Microbicides
J Biomech Eng (June,2013)
Editorial
J. Med. Devices (March,2007)
Related Chapters
Experimental Studies
Nanoparticles and Brain Tumor Treatment
Nanomaterials: A brief introduction
Biocompatible Nanomaterials for Targeted and Controlled Delivery of Biomacromolecules
Introduction
Chitosan and Its Derivatives as Promising Drug Delivery Carriers