Millions of people worldwide suffer from an involuntary leakage of urine, a condition known as urinary incontinence. In the US alone, the estimated cost of managing this is more than $16 billion [1]. Stress urinary incontinence (SUI), the most common form, is characterized by involuntary leakage of urine from effort or exertion during actions such as laughing, coughing, or sneezing. SUI largely occurs as a result of weak or damaged pelvic muscles that support the bladder and urethra, which makes the urethra unable to maintain its seal and allows urine to leak. Current SUI treatments such as pelvic floor muscle training, vaginal inserts, pharmacologic therapeutics, and surgical procedures are limited by ineffectiveness and/or subsequent complications [2, 3].
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ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Characterization of Isolated Urethral Smooth Muscle Cells and Their Incorporation Into a Tissue Engineered Urethral Wrap
Sanket N. Patel,
Sanket N. Patel
University of Pittsburgh, Pittsburgh, PA
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Donna J. Haworth,
Donna J. Haworth
University of Pittsburgh, Pittsburgh, PA
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Anton E. Xavier,
Anton E. Xavier
University of Pittsburgh, Pittsburgh, PA
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Douglas W. Chew,
Douglas W. Chew
University of Pittsburgh, Pittsburgh, PA
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David A. Vorp
David A. Vorp
University of Pittsburgh, Pittsburgh, PA
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Sanket N. Patel
University of Pittsburgh, Pittsburgh, PA
Donna J. Haworth
University of Pittsburgh, Pittsburgh, PA
Anton E. Xavier
University of Pittsburgh, Pittsburgh, PA
Douglas W. Chew
University of Pittsburgh, Pittsburgh, PA
David A. Vorp
University of Pittsburgh, Pittsburgh, PA
Paper No:
SBC2009-206253, pp. 807-808; 2 pages
Published Online:
July 19, 2013
Citation
Patel, SN, Haworth, DJ, Xavier, AE, Chew, DW, & Vorp, DA. "Characterization of Isolated Urethral Smooth Muscle Cells and Their Incorporation Into a Tissue Engineered Urethral Wrap." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 807-808. ASME. https://doi.org/10.1115/SBC2009-206253
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