Microstructurally Motivated Constitutive Models for Mouse Arteries

Vascular remodeling occurs as cells sense changes in their mechanical environment. Thus, quantifying the cells’ local environment in terms of stress and strain distributions is an important aspect in studies of vascular remodeling. Knowledge of the constitutive behavior of vessel will allow the local stresses and strains to be calculated given applied loads and geometry. The goal of this study is to determine material parameters for several constitutive models by fitting biaxial testing data from mouse carotid arteries cultured under different axial loading conditions [1].