It is known that NMR proton spin-spin (T2) or spin-lattice (T1) relaxation time measurements and analytical processing techniques have been used to determine microstructural characteristics of various types of fluid filled porous materials with characteristic pore sizes ranging from sub-micron to sub-millimeter. Currently this method has been developed and applied to quantify the porosity, pore size distribution and microdamage in human cortical bone [1–3]. The observed proton NMR relaxation signals are a convolution of the relaxation of fluid in the pores throughout the observed system with the longer relaxation time corresponding to larger pore sizes. Thus, regions within the bone matrix in which fluid may accumulate can effectively be treated as a “pore” and will be manifest as a change in the relaxation signal. Deconvolution of the relaxation signal can provide quantitative information about the relaxation distributions of fluid inside bone, i.e., the distribution of water within bone tissue. Since teeth are comprised of fluid-filled porous materials, and dentin is like bone, we also applied this rapid, non-destructive and non-invasive technique to detect and quantify age-related teeth structural changes particularly for both dentin and pulp based on broadline pulsed NMR.
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ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
The Characterization and Comparison of Human Cortical Bone and Teeth Structural Changes by Low Field NMR
Qingwen Ni,
Qingwen Ni
Southwest Research Institute, San Antonio, TX
Texas A&M International University, Laredo, TX
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Shuo Chen
Shuo Chen
University of Texas Health Science Center at San Antonio, San Antonio, TX
Search for other works by this author on:
Qingwen Ni
Southwest Research Institute, San Antonio, TX
Texas A&M International University, Laredo, TX
Shuo Chen
University of Texas Health Science Center at San Antonio, San Antonio, TX
Paper No:
SBC2009-205251, pp. 47-48; 2 pages
Published Online:
July 19, 2013
Citation
Ni, Q, & Chen, S. "The Characterization and Comparison of Human Cortical Bone and Teeth Structural Changes by Low Field NMR." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 47-48. ASME. https://doi.org/10.1115/SBC2009-205251
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