Abdominal aortic aneurysm (AAA) is a significant disease in the United States, and an intraluminal thrombus (ILT) develops in the majority of AAAs. Rupture prediction of AAA has been performed on patient specific models based on reconstruction of computed tomography (CT) images. The ILT alters stress distribution in the AAA wall [1], and ILT growth and thickness are correlated to rupture risk [2, 3]. Drug treatment of AAA is under investigation by several groups [4]. It is also known that the wall covered by the ILT is weaker than other areas [1]. If local drug delivery through the lumen is to be achieved, the barriers for transport through the ILT must be investigated. Patient specific geometries of the ILT would be necessary for such analysis.
Skip Nav Destination
ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Geometry of Abdominal Aortic Aneurysms and the Intraluminal Thrombus From 3D Image Reconstruction Using Active Contours Available to Purchase
John H. Ashton,
John H. Ashton
University of Arizona, Tucson, AZ
Search for other works by this author on:
Avinash Ayyalasomayajula,
Avinash Ayyalasomayajula
University of Arizona, Tucson, AZ
Search for other works by this author on:
Jonathan P. Vande Geest
Jonathan P. Vande Geest
University of Arizona, Tucson, AZ
Search for other works by this author on:
John H. Ashton
University of Arizona, Tucson, AZ
Avinash Ayyalasomayajula
University of Arizona, Tucson, AZ
Jonathan P. Vande Geest
University of Arizona, Tucson, AZ
Paper No:
SBC2009-206645, pp. 459-460; 2 pages
Published Online:
July 19, 2013
Citation
Ashton, JH, Ayyalasomayajula, A, & Vande Geest, JP. "Geometry of Abdominal Aortic Aneurysms and the Intraluminal Thrombus From 3D Image Reconstruction Using Active Contours." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 459-460. ASME. https://doi.org/10.1115/SBC2009-206645
Download citation file:
6
Views
Related Proceedings Papers
Related Articles
Automated Methodology for Determination of Stress Distribution in Human Abdominal Aortic Aneurysm
J Biomech Eng (October,2005)
The Association of Wall Mechanics and Morphology: A Case Study of Abdominal Aortic Aneurysm Growth
J Biomech Eng (October,2011)
Related Chapters
Experimental Studies
Nanoparticles and Brain Tumor Treatment
Chitosan-Based Drug Delivery Systems
Chitosan and Its Derivatives as Promising Drug Delivery Carriers
Conclusions
Chitosan and Its Derivatives as Promising Drug Delivery Carriers