The pathogenesis, progression and rupture of cerebral aneurysms are multi-factorial mechanisms that involve arterial hemodynamics, wall biomechanics, wall mechano-transduction or mechano-biology, and peri-aneurysmal environmental effects [1]. However, the interaction and relative importance of these factors remains poorly understood. Presumably, the geometrical shape and evolution of aneurysms are governed by the interaction between hemodynamic stimuli (wall shear stress) and the biological responses of the arterial wall. In order to better understand this interaction, the goal of this study was to characterize and relate the geometrical shapes of intracranial aneurysms at a single location, the posterior communicating artery (PComA), to blood flow patterns, wall shear stress (WSS), and clinical history of previous rupture.
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ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Aneurysms of the Posterior Communicating Artery: Hemodynamics and Shapes
Svetlana Khvostova,
Svetlana Khvostova
George Mason University, Fairfax, VA
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Christopher Putman,
Christopher Putman
Inova Fairfax Hospital, Fairfax, VA
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Juan R. Cebral
Juan R. Cebral
George Mason University, Fairfax, VA
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Svetlana Khvostova
George Mason University, Fairfax, VA
Christopher Putman
Inova Fairfax Hospital, Fairfax, VA
Juan R. Cebral
George Mason University, Fairfax, VA
Paper No:
SBC2009-206157, pp. 431-432; 2 pages
Published Online:
July 19, 2013
Citation
Khvostova, S, Putman, C, & Cebral, JR. "Aneurysms of the Posterior Communicating Artery: Hemodynamics and Shapes." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 431-432. ASME. https://doi.org/10.1115/SBC2009-206157
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