Cardiovascular disease has long been the leading cause of death in the western world: over 1.4 million heart attacks are suffered every year, more than half of which prove fatal. Vulnerable plaques are inflamed, active, and growing lesions which are prone to complications such as rupture, luminal and mural thrombosis, intraplaque hemorrhage, and rapid progression to stenosis. The rupture of thin fibrous cap overlying the necrotic core of a vulnerable plaque is the principal cause of acute coronary syndrome. The mechanism or mechanisms responsible for the sudden conversion of a stable atherosclerotic plaque to a life threatening athero-thrombotic lesion are not fully understood. It has been widely assumed that plaque morphology is the major determinant of clinical outcome [1, 2].
Skip Nav Destination
ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Analysis of Biomechanical Forces Influencing Atherosclerotic Plaque Vulnerability
Ze’ev Aronis,
Ze’ev Aronis
Tel Aviv University, Tel-Aviv, Israel
Search for other works by this author on:
Shmuel Einav
Shmuel Einav
State University of New York at Stony Brook, Stony Brook, NY
Search for other works by this author on:
Ze’ev Aronis
Tel Aviv University, Tel-Aviv, Israel
Shmuel Einav
State University of New York at Stony Brook, Stony Brook, NY
Paper No:
SBC2009-206454, pp. 183-184; 2 pages
Published Online:
July 19, 2013
Citation
Aronis, Z, & Einav, S. "Analysis of Biomechanical Forces Influencing Atherosclerotic Plaque Vulnerability." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 183-184. ASME. https://doi.org/10.1115/SBC2009-206454
Download citation file:
6
Views
Related Proceedings Papers
Related Articles
Porohyperelastic Finite Element Modeling of Abdominal Aortic Aneurysms
J Biomech Eng (October,2010)
Anisotropic Mechanical Properties of Tissue Components in Human Atherosclerotic Plaques
J Biomech Eng (October,2004)
Automated Methodology for Determination of Stress Distribution in Human Abdominal Aortic Aneurysm
J Biomech Eng (October,2005)
Related Chapters
Occlusion Identification and Relief within Branched Structures
Biomedical Applications of Vibration and Acoustics in Therapy, Bioeffect and Modeling
Introduction
Modified Detrended Fluctuation Analysis (mDFA)
Introduction
Mechanical Blood Trauma in Circulatory-Assist Devices