Atherosclerosis in the carotid bifurcation is a highly variable disease that, in its stable form, can cause a dangerous reduction of blood flow to the brain. If the plaque ruptures or ulcerates, the patient is likely to experience a thrombotic or embolic stroke. Stroke is the 3rd leading cause of death in the western world, and approximately 10–15% of these cases develop from carotid atherosclerosis . In addition to the complex biochemistry involved in the initiation, progression, and acute insult of carotid disease, the mechanical environment of the carotid bifurcation may also play a pivotal role in these disease states.
- Bioengineering Division
Patient Specific FEM Analysis of the Atherosclerotic Carotid Bifurcation
Leach, JR, Rayz, VL, Mofrad, MRK, Wintermark, M, & Saloner, D. "Patient Specific FEM Analysis of the Atherosclerotic Carotid Bifurcation." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 177-178. ASME. https://doi.org/10.1115/SBC2009-206828
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