Atherosclerotic plaque vulnerability assessment and the ability to predict possible future rupture are of vital importance for early diagnosis, prevention and treatment of cardiovascular diseases related to atherosclerosis. It has been hypothesized that critical stress conditions in the plaque may be closely related to plaque rupture and can be combined with current image-based assessment techniques for more accurate plaque evaluation. A major challenge for all available plaque assessment schemes is the lack of gold standard based on in vivo patient data where both ruptured and non-ruptured plaques were compared and analyzed. In vivo patient image data showing rupture verified by histological information (current gold standard) provided by excised specimens data will help to establish in vivo benchmark for image-based and/or stress-based assessment schemes.
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ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
Atherosclerotic Carotid Plaques With Prior Rupture Are Associated With Higher Structural Stresses: In Vivo MRI-Based 3D FSI Studies
Zhongzhao Teng,
Zhongzhao Teng
Worcester Polytechnic Institute, Worcester, MA
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Joseph D. Petruccelli,
Joseph D. Petruccelli
Worcester Polytechnic Institute, Worcester, MA
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Xueying Huang,
Xueying Huang
Worcester Polytechnic Institute, Worcester, MA
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Chun Yang,
Chun Yang
Beijing Normal University, Beijing, China
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Zijie Liao,
Zijie Liao
Worcester Polytechnic Institute, Worcester, MA
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Chun Yuan,
Chun Yuan
University of Washington, Seattle, WA
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Thomas Hatsukami,
Thomas Hatsukami
University of Washington, Seattle, WA
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Gador Canton,
Gador Canton
University of Washington, Seattle, WA
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Marina Ferguson,
Marina Ferguson
University of Washington, Seattle, WA
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Jie Zheng,
Jie Zheng
Washington University in St. Louis, St. Louis, MO
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Pamela K. Woodard,
Pamela K. Woodard
Washington University in St. Louis, St. Louis, MO
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Dalin Tang
Dalin Tang
Worcester Polytechnic Institute, Worcester, MA
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Zhongzhao Teng
Worcester Polytechnic Institute, Worcester, MA
Joseph D. Petruccelli
Worcester Polytechnic Institute, Worcester, MA
Xueying Huang
Worcester Polytechnic Institute, Worcester, MA
Chun Yang
Beijing Normal University, Beijing, China
Zijie Liao
Worcester Polytechnic Institute, Worcester, MA
Chun Yuan
University of Washington, Seattle, WA
Thomas Hatsukami
University of Washington, Seattle, WA
Gador Canton
University of Washington, Seattle, WA
Marina Ferguson
University of Washington, Seattle, WA
Jie Zheng
Washington University in St. Louis, St. Louis, MO
Pamela K. Woodard
Washington University in St. Louis, St. Louis, MO
Dalin Tang
Worcester Polytechnic Institute, Worcester, MA
Paper No:
SBC2009-204708, pp. 169-170; 2 pages
Published Online:
July 19, 2013
Citation
Teng, Z, Petruccelli, JD, Huang, X, Yang, C, Liao, Z, Yuan, C, Hatsukami, T, Canton, G, Ferguson, M, Zheng, J, Woodard, PK, & Tang, D. "Atherosclerotic Carotid Plaques With Prior Rupture Are Associated With Higher Structural Stresses: In Vivo MRI-Based 3D FSI Studies." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 169-170. ASME. https://doi.org/10.1115/SBC2009-204708
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