Transdermal drug delivery (TDD) is a promising alternative to conventional drug delivery approaches, such as oral or injectable routes. In comparison, the primary benefits of TDD include [1]: 1) avoidance of first pass metabolism and other variables associated with the GI tract such as pH changes and gastric emptying time. 2) sustained and controlled delivery over a prolonged period of time. 3) reduction in side effects associated with systemic toxicity. 4) improved patient acceptance and compliance. 5) direct access to targeted or diseased site, e.g. treatment of skin disorders. 6) ease of dose termination in the event of any adverse reactions either systemic or local; 7) convenient and painless administration; 8) ease of use and reduction of overall health care treatment costs; 9) viable alternative in circumstances where oral dosing is not possible (in unconscious or nauseated patients).
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ASME 2009 Summer Bioengineering Conference
June 17–21, 2009
Lake Tahoe, California, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4891-3
PROCEEDINGS PAPER
An Experimental Study of In Vitro Transdermal Drug Delivery Assisted by Cryopneumatic Technology Available to Purchase
Feng Sun,
Feng Sun
University of California, Riverside, Riverside, CA
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Robert Anderson,
Robert Anderson
Aesthera Corp., Pleasanton, CA
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Guillermo Aguilar
Guillermo Aguilar
University of California, Riverside, Riverside, CA
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Feng Sun
University of California, Riverside, Riverside, CA
Robert Anderson
Aesthera Corp., Pleasanton, CA
Guillermo Aguilar
University of California, Riverside, Riverside, CA
Paper No:
SBC2009-204240, pp. 1259-1260; 2 pages
Published Online:
July 19, 2013
Citation
Sun, F, Anderson, R, & Aguilar, G. "An Experimental Study of In Vitro Transdermal Drug Delivery Assisted by Cryopneumatic Technology." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 1259-1260. ASME. https://doi.org/10.1115/SBC2009-204240
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