The influence of mechanical stresses on cells has been a topic of special interest . Attention is being focused on the cell-to-cell and cell-to-surrounding interactions and the mechanical stimuli that could be directly linked with functional adaption and pathological conditions of each cell or cluster of cells . The aim of this research is to understand the biomechanical roles of cellular junctions on epithelial cells, exposed to a large multidirectional and uniform strain, using a microballoon (MB) platform. Quantitative measurement on strain values can be used to determine the necessary strains at which intercellular and cell-to-substrate connections are disassembled. This will provide information for characterizing cell-to-cell and cell-to-substrate adhesions during biological development and/or diseases.
- Bioengineering Division
MEMS-Based Microballoons Achieving Multidirectional Large-Strain for Cell Mechanics Studies
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Yoon, S, Reyes-Ortiz, V, & Mofrad, MRK. "MEMS-Based Microballoons Achieving Multidirectional Large-Strain for Cell Mechanics Studies." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 1163-1164. ASME. https://doi.org/10.1115/SBC2009-206853
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