Non-Thermal Atmospheric Pressure Dielectric Barrier Discharge Plasma Enhances Endothelial Cell Proliferation via Fibroblast Growth Factor-2 Release

Cold atmospheric pressure plasma is currently being investigated for a wide range of clinical applications, including skin sterilization, blood coagulation [1, 2], malignant cell apoptosis [1], and wound healing [1]. However, the effect of non-thermal plasma on the vasculature is unclear. Blood vessels are affected during plasma treatment of all tissues, and vessels themselves may be an important potential target for clinical plasma therapy.