A Structure-Based Model of Arterial Remodeling in Response to Sustained Hypertension

Pressure-induced remodeling of arteries is an adaptive process, which restores the magnitude of media tensile stress and intimal shear stress to their baseline values under normotensive conditions [1]. Revealing the role that mechanical factors play in arterial adaptation is important for understanding the normal arterial function as well as the pathogenesis of various arterial diseases.