The link between hemodynamic forces, notably wall shear stress (WSS), and atherogenesis is well established. Patient-specific computational fluid dynamics (CFD) modeling of human vasculature has attracted recent attention because it allows investigators to determine areas at risk for plaque formation and subsequent rupture . Non-invasive in vivo imaging methods such as magnetic resonance (MR) angiography allow acquisition of vascular geometry and cross-sectional velocity such that a CFD model can determine the spatial distribution of WSS. WSS may then be correlated with phenomena such as wall thickening.
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Inter-Operator Segmentation Differences Impact Wall Shear Stress Distributions in Patient-Specific Computational Fluid Dynamic Models
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Campbell, IC, Sprague, WW, Piccinelli, M, Veneziani, A, & Oshinski, JN. "Inter-Operator Segmentation Differences Impact Wall Shear Stress Distributions in Patient-Specific Computational Fluid Dynamic Models." Proceedings of the ASME 2009 Summer Bioengineering Conference. ASME 2009 Summer Bioengineering Conference, Parts A and B. Lake Tahoe, California, USA. June 17–21, 2009. pp. 1017-1018. ASME. https://doi.org/10.1115/SBC2009-206150
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