Meniscectomy is a well-known risk factor for osteoarthritis (OA) in humans. It has been reported that total meniscectomy increases the risk of developing osteoarthritis radiographically by 14 times after 21 years  and that partial meniscectomy increases the risk of developing radiographic evidence of osteoarthritis within 16 years by a factor of four . Two possible functional measures have been suggested as mechanisms for the development and progression of premature knee osteoarthritis: alterations in either kinematics or kinetics. Changes in kinematics, such as a shift in internal-external (IE) rotation after anterior cruciate ligament injury, have been suggested as a basis for an increased rate of cartilage thinning . The other possible reason for the development of premature OA post-meniscectomy is a change in kinetics, the mechanical loading that occurs, particularly in the medial compartment . The knee adduction moment has been associated with the rate of progression of osteoarthritis  and it has thus been suggested that the knee adduction moment is a good surrogate measure for in vivo load on the medial compartment osteoarthritis .
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Changes in Tibiofemoral Kinematics and Kinetics During Stair Ascent After Partial Medial Meniscectomy
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Netravali, NA, & Andriacchi, TP. "Changes in Tibiofemoral Kinematics and Kinetics During Stair Ascent After Partial Medial Meniscectomy." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 813-814. ASME. https://doi.org/10.1115/SBC2008-192515
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