The development of bone replacement materials for large and load-bearing defects and their translation to the clinic will require extensive characterization of the mechanical properties of the scaffold/bone composites after implantation. Numerous of challenges are associated with such characterization of these types of composite. In particular, the need for large animal models, the associated cost, and the removal of the scaffolds from host bone for mechanical testing are some of the more difficult challenges to overcome. The ability to accurately predict the mechanical properties of scaffold/bone composites will lead to significant advances in the area of bone tissue engineering. Properties for periodic materials have been accurately modeled modeled using representative volume elements (RVE) [1]. The hydroxyapatite (HA) scaffolds in this study have a periodic lattice structure, making the use of an RVE appropriate for modeling effective properties. However, the choice of an appropriate RVE and geometry to represent the bone in the composite is less clear.
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ASME 2008 Summer Bioengineering Conference
June 25–29, 2008
Marco Island, Florida, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4321-5
PROCEEDINGS PAPER
Bone Geometry in Periodic Hydroxyapatite Scaffolds Has Little Influence on Effective Elastic Properties Available to Purchase
Amy J. Wagoner Johnson,
Amy J. Wagoner Johnson
University of Illinois at Urbana-Champaign, Urbana, IL
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Lucas McInstosh,
Lucas McInstosh
University of Illinois at Urbana-Champaign, Urbana, IL
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Jackie M. Cordell
Jackie M. Cordell
University of Illinois at Urbana-Champaign, Urbana, IL
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Amy J. Wagoner Johnson
University of Illinois at Urbana-Champaign, Urbana, IL
Lucas McInstosh
University of Illinois at Urbana-Champaign, Urbana, IL
Jackie M. Cordell
University of Illinois at Urbana-Champaign, Urbana, IL
Paper No:
SBC2008-193229, pp. 711-712; 2 pages
Published Online:
March 13, 2014
Citation
Wagoner Johnson, AJ, McInstosh, L, & Cordell, JM. "Bone Geometry in Periodic Hydroxyapatite Scaffolds Has Little Influence on Effective Elastic Properties." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 711-712. ASME. https://doi.org/10.1115/SBC2008-193229
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