The operating pressures in the right heart are significantly lower than those of the left heart and with marked differences in the circulation impedances. The pulmonary circulation shows a tolerance for mild regurgitation and pressure gradient . Pulmonary regurgitation fractions on the order of 20% and transvalvular pressure gradients of less than 25mm Hg are considered mild . Given this tolerance, we examine the concept of using a motionless valve to regulate flow in the pulmonary position. In a previous study, the use of fluid diodes was shown to be a promising concept for use as a pulmonary valve . In this study, we test a fluid diode both in a bench top circulatory system  and in a swine model and compare the pressure gradients and regurgitant fractions.
- Bioengineering Division
Comparison of In Vitro and In Vivo Testing of Fluid Diodes as a Pulmonary Heart Valve Replacement
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Camp, T, Figliola, R, McQuinn, T, Hsia, T, & Conover, T. "Comparison of In Vitro and In Vivo Testing of Fluid Diodes as a Pulmonary Heart Valve Replacement." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 677-678. ASME. https://doi.org/10.1115/SBC2008-193156
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