The operating pressures in the right heart are significantly lower than those of the left heart and with marked differences in the circulation impedances. The pulmonary circulation shows a tolerance for mild regurgitation and pressure gradient [1]. Pulmonary regurgitation fractions on the order of 20% and transvalvular pressure gradients of less than 25mm Hg are considered mild [2]. Given this tolerance, we examine the concept of using a motionless valve to regulate flow in the pulmonary position. In a previous study, the use of fluid diodes was shown to be a promising concept for use as a pulmonary valve [3]. In this study, we test a fluid diode both in a bench top circulatory system [4] and in a swine model and compare the pressure gradients and regurgitant fractions.
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ASME 2008 Summer Bioengineering Conference
June 25–29, 2008
Marco Island, Florida, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4321-5
PROCEEDINGS PAPER
Comparison of In Vitro and In Vivo Testing of Fluid Diodes as a Pulmonary Heart Valve Replacement Available to Purchase
Tiffany Camp,
Tiffany Camp
Clemson University, Clemson, SC
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Richard Figliola,
Richard Figliola
Clemson University, Clemson, SC
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Tim McQuinn,
Tim McQuinn
Medical University of South Carolina, Charleston, SC
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T.-Y. Hsia,
T.-Y. Hsia
Medical University of South Carolina, Charleston, SC
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Tim Conover
Tim Conover
Clemson University, Clemson, SC
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Tiffany Camp
Clemson University, Clemson, SC
Richard Figliola
Clemson University, Clemson, SC
Tim McQuinn
Medical University of South Carolina, Charleston, SC
T.-Y. Hsia
Medical University of South Carolina, Charleston, SC
Tim Conover
Clemson University, Clemson, SC
Paper No:
SBC2008-193156, pp. 677-678; 2 pages
Published Online:
March 13, 2014
Citation
Camp, T, Figliola, R, McQuinn, T, Hsia, T, & Conover, T. "Comparison of In Vitro and In Vivo Testing of Fluid Diodes as a Pulmonary Heart Valve Replacement." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 677-678. ASME. https://doi.org/10.1115/SBC2008-193156
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