The stiffness and strength of a healing bone fracture depend on the geometry of the fracture callus as well as the mechanical properties of the callus tissues. In the clinical setting, the mechanical stability of a healing fracture is often estimated qualitatively based on the radioopacity of the callus tissue. However, a quantitative association between tissue mineralization and mechanical properties has yet to be established for these tissues. Quantifying callus tissue material properties and mineral content may therefore enable improved non-invasive assessments of bone healing. In addition, elucidating relationships between callus tissue composition and function will provide a means of understanding the mechanism by which the injured bone recovers its mechanical integrity.
- Bioengineering Division
Correlation Between Nanoindentation Modulus and Mineral Density in Fracture Callus Tissues
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Leong, PL, & Morgan, EF. "Correlation Between Nanoindentation Modulus and Mineral Density in Fracture Callus Tissues." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 675-676. ASME. https://doi.org/10.1115/SBC2008-193149
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