The aortic root is the portion of the outflow tract of the left ventricle that includes the aortic leaflets, the aortic annulus, the sinuses of Valsalva and the sinotubular junction. The impairment of one or more of these structures can lead not only to dysfunctions of the root, but also to alterations of the adjacent anatomical sites, such as the ascending aorta. The raise and the progress of the alterations are often related to more concomitant factors, whose separated effect can be difficult to assess. At this purpose computational finite element (FE) models can be a useful tool, given their capability the recreate different scenarios by varying one or more parameters of the model in a controlled fashion.

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