Porous polymeric materials play a key role in regenerative medicine, serving as three-dimensional scaffolds for cell culture. Hence, the definition of their micro-architecture should be regarded as a pivotal design issue, that has to be wittingly addressed while engineering a cell culture system. Computational fluid dynamics techniques (CFD) appear to be very valuable in this respect, since they have been appreciably applied in recent literature as a means to analyze fluid dynamics and mass transport inside scaffold or bioreactor models ; moreover, leading researchers in tissue engineering have acknowledged the role of numerical methodology in the issue of defining optimal flow conditions for three-dimensional dynamic culture systems.
- Bioengineering Division
Metabolite Transport Inside Channeled Porous Scaffolds for Haematopoietic Stem Cell Culture: A Computational Study
Cantini, M, Fiore, GB, Redaelli, A, & Soncini, M. "Metabolite Transport Inside Channeled Porous Scaffolds for Haematopoietic Stem Cell Culture: A Computational Study." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 481-482. ASME. https://doi.org/10.1115/SBC2008-192852
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