It is well established that atherosclerosis originates in low wall shear stress (WSS) regions near bifurcations and in curved segments of the coronary tree . WSS also seems to influences plaque progression and destabilization, which explains the large interest in accurate assessment of the WSS.
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Comparison of Outflow Condition Models on the Effect of Wall Shear Stress Distribution in Patient Specific Coronary Trees
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van der Giessen, AG, Gijsen, FJH, Wentzel, JJ, Groen, HC, van der Steen, AFW, & van de Vosse, FN. "Comparison of Outflow Condition Models on the Effect of Wall Shear Stress Distribution in Patient Specific Coronary Trees." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 45-46. ASME. https://doi.org/10.1115/SBC2008-192774
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