Cardiovascular disease has historically been the leading cause of death in the US [1], and accounts for approximately one third of all deaths worldwide [2]. Coronary artery disease in particular accounts for over fifty percent of these deaths and in 2004 was the single largest killer, affecting approximately 15 million people every year [1]. Coronary stenting was approved in 1994 by the FDA, and has become one of the leading treatments for the disease. However, problems persist in both bare metal and drug-eluting stents (DESs) with restenosis and thrombosis. It is well accepted that disruptions in arterial wall shear stress (WSS), especially low WSS, are linked to alterations in the endothelial cell layer and ultimately disease [3], although the exact mechanisms are still uncertain. Additionally, studies have shown that stent design is closely linked to clinical outcomes [4].
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ASME 2008 Summer Bioengineering Conference
June 25–29, 2008
Marco Island, Florida, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
978-0-7918-4321-5
PROCEEDINGS PAPER
A Time Resolved DPIV In-Vitro Evaluation of Coronary Stents in Realistic Conditions: Part II — Effect of Stent Design
John J. Charonko,
John J. Charonko
Virginia Tech, Blacksburg, VA
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Satya P. Karri,
Satya P. Karri
Virginia Tech, Blacksburg, VA
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Jaime Schmieg,
Jaime Schmieg
Virginia Tech, Blacksburg, VA
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Santosh V. Prabhu,
Santosh V. Prabhu
Abbott Vascular, Santa Clara, CA
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Pavlos P. Vlachos
Pavlos P. Vlachos
Virginia Tech, Blacksburg, VA
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John J. Charonko
Virginia Tech, Blacksburg, VA
Satya P. Karri
Virginia Tech, Blacksburg, VA
Jaime Schmieg
Virginia Tech, Blacksburg, VA
Santosh V. Prabhu
Abbott Vascular, Santa Clara, CA
Pavlos P. Vlachos
Virginia Tech, Blacksburg, VA
Paper No:
SBC2008-192646, pp. 391-392; 2 pages
Published Online:
March 13, 2014
Citation
Charonko, JJ, Karri, SP, Schmieg, J, Prabhu, SV, & Vlachos, PP. "A Time Resolved DPIV In-Vitro Evaluation of Coronary Stents in Realistic Conditions: Part II — Effect of Stent Design." Proceedings of the ASME 2008 Summer Bioengineering Conference. ASME 2008 Summer Bioengineering Conference, Parts A and B. Marco Island, Florida, USA. June 25–29, 2008. pp. 391-392. ASME. https://doi.org/10.1115/SBC2008-192646
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