A New Method of Blunt Cartilage Impact for a Model of Osteoarthritis

Impact injury to cartilage, a common consequence of joint trauma, is commonly thought to lead to degenerative osteoarthritis. Many pharmacologic agents have been developed to prevent or forestall this process. Development of a reliable model for the early stages of cartilage injury and osteoarthritis would enable the testing of novel treatments that could delay or even reverse the progression of this debilitating disease.