Mechanical force is believed to play a significant role in regulating the morphogenetic process of cardiac looping. To better understand this process, it is crucial to determine the material properties of the early chick heart. It is well known that biological tissues are viscoelastic, however previous data on early stage embryonic heart tissue shows a hyperelastic behavior only [1] and currently, only late stage heart tissues have been quantified using viscoelastic properties [2]. The objective of this study is to use microindentation and nonlinear finite element method (FEM) to characterize the viscoelastic material properties of stage 12 chick heart during cardiac looping.

This content is only available via PDF.
You do not currently have access to this content.