In many areas of orthopaedic biomechanics, such as implant design, properly developed Finite Element (FE) models can be a great companion to in-vitro studies, as they may allow a wider range of experimental variables to be explored in a cost-effective and timely manner. One challenge in developing these models is the assignment of accurate material properties to bone. Through the use of computed tomography (CT), many recent studies have developed subject-specific FE models, where material properties of bone are assigned based on density information derived from the scans. This involves the use of an equation to relate density and elastic modulus. There are several such relationships from which to choose in the literature. Most FE studies tend to use one of these multiple equations without justification or investigation into its appropriateness for the model.

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