The 70cc LionHeart was developed for use in patients weighing more than 70 kg, which prevents its use in many women, smaller men, and children. Scaled-down devices have been prone to thrombus formation during animal testing [1, 2]. It is suspected that the increased level of thrombosis is related to changes in the flow field when scaling from the 70cc to the 50cc device. Low fluid shear stresses and high residence times are traits that are believed to influence thrombus formation and deposition within artificial blood pumps [1].

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