Diffuse brain injury (DBI) severity can be clinically diagnosed as concussion or diffuse axonal injury (DAI). Concussion the least severe DBI, is associated with neurological deficit limited to disorientation and unconsciousness lasting minutes to hours [1–4]. In contrast, DAI, a severe injury, commonly results in death or permanent vegetation [1]. It is generally accepted that injury severity is modulated by increased mechanical measures such as rotational acceleration and velocity [5–11].

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