Development of 4-D High-Resolution CT for Measurement of Airway Deformation

Airway consists of a number of various compliant tubes from trachea to alveolus, and the airway geometry deforms dramatically during respiration. This morphometric deformation is very important factors in pulmonary dynamics (flow structure, particle deposition, surfactant transport and so on). Previously, we reported the small airway deformations of euthanized animals using micro-CT and synchrotron radiation-CT.