As the most common congenital heart defect, bicuspid aortic valve (BAV) occurs in 1–2 % of the population and has been associated with serious complications such as aortic valve dysfunction, infective endocarditis, aortic dilatation, aortic aneurysm, and aortic dissection [1, 2]. While the pathogenesis of this valve malformation has been postulated to be genetic, the resulting vascular environment and abnormal hemodynamics are hypothesized to contribute to the progression of the disease and its subsequently high morbidity and mortality (greater than 33% of patients with BAV develop serious complications from the disease) [1]. However, clinical details supporting the causality between altered local blood flow dynamics and development of structural abnormality at the aortic root are still lacking.
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ASME 2007 Summer Bioengineering Conference
June 20–24, 2007
Keystone, Colorado, USA
Conference Sponsors:
- Bioengineering Division
ISBN:
0-7918-4798-5
PROCEEDINGS PAPER
Use of Cardiac Phase-Contrast MRI to Examine Hemodynamics and Wall Deformation Within the Aortic Root for Patients With Bicuspid Aortic Valves Available to Purchase
Alex J. Barker,
Alex J. Barker
University of Colorado, Boulder, CO
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Craig Lanning,
Craig Lanning
The Children’s Hospital, Denver, CO
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Devatha Nair,
Devatha Nair
University of Colorado, Boulder, CO
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Vernon Chapman,
Vernon Chapman
Radiology Imaging Associates, Englewood, CO
The Children’s Hospital, Denver, CO
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Robin Shandas
Robin Shandas
University of Colorado, Boulder, CO
The Children’s Hospital, Denver, CO
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Alex J. Barker
University of Colorado, Boulder, CO
Craig Lanning
The Children’s Hospital, Denver, CO
Devatha Nair
University of Colorado, Boulder, CO
Vernon Chapman
Radiology Imaging Associates, Englewood, CO
The Children’s Hospital, Denver, CO
Robin Shandas
University of Colorado, Boulder, CO
The Children’s Hospital, Denver, CO
Paper No:
SBC2007-176432, pp. 507-508; 2 pages
Published Online:
March 12, 2014
Citation
Barker, AJ, Lanning, C, Nair, D, Chapman, V, & Shandas, R. "Use of Cardiac Phase-Contrast MRI to Examine Hemodynamics and Wall Deformation Within the Aortic Root for Patients With Bicuspid Aortic Valves." Proceedings of the ASME 2007 Summer Bioengineering Conference. ASME 2007 Summer Bioengineering Conference. Keystone, Colorado, USA. June 20–24, 2007. pp. 507-508. ASME. https://doi.org/10.1115/SBC2007-176432
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