Geometry Anticipates Hemodynamic Phenotype of Basilar Tip Aneurysms Available to Purchase

The prevalence of unruptured cerebral aneurysms is estimated to be as high as 5% [1]. Basilar tip aneurysms account for 4–5% of these, but have a higher risk of rupture [2]. They are also difficult to treat surgically, and so endovascular therapy is often the only option. Hemodynamic forces have been implicated in the risk of rupture [3] and complications of endovascular therapy [4]; however, hemodynamic information is difficult to acquire clinically. Computational fluid dynamics (CFD), in combination with clinical imaging, can be used to accurately capture the intra-aneurysmal hemodynamics in a patient-specific manner [5]. Still, these techniques have not translated to routine clinical use, largely due to the time and effort required to construct, simulate, and interpret these models.