Trabecular bone fracture is closely related to the trabecular architecture and microdamage accumulation. Micro-finite element models have been used to investigate the elastic and yield properties of trabecular bone but have only seen limited application in modeling the microstructure dependent fracture of trabecular bone, [1, 2]. In the presented research a cohesive finite element method (CFEM) based approach that can be used to model microstructure and loading rate dependent fracture in trabecular bone is developed for the first time. The emphasis is on understanding the effect of the rate of loading and its correlation with the bone microstructure on the microdamage accumulation and fracture behavior in the trabecular bone. Analyses focus on understanding the effect of the rate of loading, change in bone tissue properties with aging, and their correlation with the bone microstructure on the microdamage accumulation and the fracture behavior in the trabecular bone.

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