Effects of Reduced Compliance on Endothelial Functionality With Regards to Inflammation and Adhesion

Among other things, the aging process is associated with a stiffening of the arteries, initiating the development of systolic hypertension and a significant increase in pulse pressure. Amplified pulse pressure has been linked to problems causing arterial dysfunction. In this study we focused on how reduced wall compliance induces pulse pressure-mediated changes in endothelial function with regards to inflammation and adhesion.