Since steam generators are used, many experiments have been performed to understand the different phenomena appearing in them. One of the main issues to reproduce a similar flow on a reduced-scale experiment is the choice of the two-phase mixture. Air/water and boiling freon are among the most used two-phase flow mixtures. In the present document, a finite-volume CFD code dedicated to multi-phase flows based on a two-fluid approach (extended to n) is used to compare two mixtures numerically. Thanks to two experiments, an air/water horizontal channel and a freon/freon inclined tube bundle, a first part highlights the validity of the two-phase flow modeling. Then, based on inlet superficial velocities from both experiments, a numerical experiment is performed by using each mixture on the other experiment. Void fraction profiles and two-phase flow regimes are compared in order to exhibit the behaviors of both mixtures in a steam generator like tube bundle. Results turn out to provide useful information (void fraction profiles mainly) about mixture properties, and near-wall loads in the vicinity of cylinders are investigated.

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