The study investigates the pullout strength of self-tapping pedicle screws using analytical, finite element, and experimental methodologies with focus on medical device applications. The stress distribution and failure propagation around implant threads in the synthetic bone during the pullout process, as well as the pullout strength of pedicle screws, are explored. Based on the FEA results, an analytical model for the pullout strength of the pedicle screw is constructed in terms of the synthetic bone material properties, screw size, and implant depth. The characteristics of pullout behavior of self-tapping pedicle screws are discussed. Both the analytical model and finite element results are validated using experimental techniques.

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