This paper provides V-factor estimation under combined mechanical and thermal load for circumferential cracked pipes. In this study, the effects of types and magnitudes of the thermal stress, mechanical loading mode, crack geometry, and plastic strain hardening on variations of V-factor are estimated. The results of finite element analyses are compared with R6 values. As a result, it is shown that R6 gives generally conservative results. The conservatism is especially increased for the combination of large mechanical and thermal load. As a result, new estimation equation which uses failure assessment curve in R6 is proposed for V-factor and gives less conservative results.

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