Besides the shock wave load and the gas bubble pulse load, cavitation effect has a significant influence on the ships subjected to underwater explosion. The goal of this research is to investigate the cavitation effect on the response of ship section using acoustic-structural arithmetic. Comparison between the structure response considering the cavitation effect and not, the formation mechanism of cavitation zone are discussed. The simulation results show acoustic-structural arithmetic can be used to numerical simulate the dynamic response of simple structure and ship section subjected to underwater explosion with the consideration of cavitation effect. And it also can be used to capture the cavitation in the water. Meanwhile, the simulation results show that cavitation zone generated by underwater explosion is very large, and the reloading effect is obvious with the consideration of cavitation effect. The vibration of the ship structure is more severe with the reloading, and thus more serious damage occurs as the result of the prolonged loading time.

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