A critical challenge in the field of medicine is to develop a low cost sensor competent of detecting specific bacterial pathogens via a precise deoxyribonucleic acid (DNA) sequence. In order to identify such biological agents in a patient’s blood or other bodily fluids at the onset of infection, detection of specific pathogen genomic DNA is considered a reliable approach. Current techniques involving multiplex DNA/RNA detection arrays or immunoassays  require cumbersome sample preparation, aggressive nucleic acid amplification protocols and must be operated by trained personnel. To overcome the aforementioned obstacles, a time-dependent dielectrophoretic force driven sensor consisting of nanostructured tip is being developed.
- ASME Nanotechnology Council
Design and Optimization of a Nanotip Sensor via Immersed Molecular Electrokinetic Finite Element Method
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Kopacz, AM, Liu, WK, & Chung, J. "Design and Optimization of a Nanotip Sensor via Immersed Molecular Electrokinetic Finite Element Method." Proceedings of the ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. ASME 2010 First Global Congress on NanoEngineering for Medicine and Biology. Houston, Texas, USA. February 7–10, 2010. pp. 59-60. ASME. https://doi.org/10.1115/NEMB2010-13299
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